Oral care composition, and preparation method and application thereof

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United States of America Patent

PATENT NO 12121611
APP PUB NO 20240269072A1
SERIAL NO

18571259

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Abstract

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The present disclosure provides an oral care composition and a preparation method, and an application thereof. The composition includes: a drug-loaded micelle, wherein the drug-loaded micelle includes a polymer micelle and an enamel restoration drug physically wrapped in the polymer micelle, and the polymer micelle is micelle particles formed by a water-soluble polymer with a structure shown by Formula I in an aqueous solution with presence of tannic acid and the micelle particles have a shell connected to a salivary protein polypeptide through chemical bonds. The oral care composition in the present disclosure enables the salivary protein polypeptide to adhere to the surfaces of teeth so as to open the borate ester bond between the tannic acid and the water-soluble polymer in an acidic environment generated by the dental caries and release the tannic acid and sodium fluoride, thus achieving the purpose of preventing dental caries and restoring tooth defects.

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Patent Owner(s)

Patent OwnerAddress
WUHAN UNIVERSITY430072 HUBEI CITY OF WUHAN PROVINCE WUCHANG LUOJIASHAN WUHAN CITY HUBEI PROVINCE 430072

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Guo, Jingmei Hubei, CN 3 0
Huang, Cui Hubei, CN 8 3
Xu, Yue Hubei, CN 72 1673

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