Materials and methods for treatment with oncolytic viruses and modified CAR T cells

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United States of America Patent

PATENT NO 12121554
APP PUB NO 20210275615A1
SERIAL NO

17275713

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Abstract

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This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (OVs) in combination with an adoptive cell therapy (e.g., a chimeric antigen receptor T cell therapy) to alter one or more functions of a T cell and/or to enhance T cell expansion to treat cancer in a mammal (e.g., a human) are provided.

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Patent Owner(s)

Patent OwnerAddress
DUKE UNIVERSITY2812 ERWIN RD STE 406 DURHAM NC 27705

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Evgin, Laura Rochester, US 6 0
Sanchez-Perez, Luis Apex, US 2 0
Vile, Richard G Rochester, US 17 136

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