Methods for evaluating tumor cell spheroids using 3D microfluidic cell culture device
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United States of America Patent
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Oct 15, 2024
Grant Date -
Nov 25, 2021
app pub date -
Jul 19, 2021
filing date -
Mar 31, 2017
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Abstract
Methods are provided for evaluating tumor cell spheroids in a three-dimensional microfluidic device by determining changes in the relative levels of live cells and dead cells in aliquots cultured under different conditions. Methods are also described for allowing ex vivo recapitulation of the tumor microenvironment such that the in vivo effectiveness of a test compound in treating tumor tissue may be predicted.
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