Vortex generator for agitation of fluids during sample preparation
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United States of America Patent
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Oct 15, 2024
Grant Date -
Oct 5, 2023
app pub date -
Jun 2, 2023
filing date -
Mar 13, 2020
priority date (Note) -
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Abstract
An apparatus, vortex generator assembly and method for automated cell lysis and nucleic acid purification and processing. The vortex generator assembly includes sample holder having a lysis well, at least one wash well, and an elution well. The vortex generator assembly also includes a sample holder cover having a plurality of vibration rods for creating a vortex in the wells of the sample holder. The apparatus includes motor operating a rotating cam to cause the vibration rods to vibrate and create the vortex in a well holding fluid and magnetic beads, wherein the vortexing speed is sufficient to overcome the magnetic attraction between the beads and disperse the beads in solution, to collect nucleic acids such as DNA.
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