Method of manufacturing a recombinant polypeptide

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United States of America Patent

PATENT NO 12116559
APP PUB NO 20220364036A1
SERIAL NO

17559366

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Abstract

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We have modified a commercially-available adherent cell culture bioreactor in several ways to increase productivity of cultured cells, while decreasing contamination risk. We found that modifying a commercially-available adherent cell culture bioreactor to provide for slower cell culture medium flow unexpectedly and dramatically increases the productivity of the cultured adherent cells. We also developed a new sampling manifold configuration and new way of taking samples, to reduce contamination risk.

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Patent Owner(s)

Patent OwnerAddress
TRIZELL LTDSANDERUM HOUSE OAKLEY ROAD CHINNOR OX39 4TW

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Karhinen, Minna Kristiina Kuopio, FI 4 12
Lesch, Hanna P Kuopio, FI 13 32
Rasanen, Eva Kristiina Hiltulanlahti, FI 4 12
Tuunanen, Tarja Hannele Kuopio, FI 4 12
Valonen, Piia Kristiina Kuopio, FI 4 12
Ylä-Herttuala, Seppo Kuopio, FI 5 1

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