Growth-independent inhibition of aflatoxin biosynthesis with selected nanoparticles

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United States of America Patent

PATENT NO 12108764
APP PUB NO 20180255784A1
SERIAL NO

15911327

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Abstract

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Methods for inhibiting fungal secondary metabolisms are described. Secondary metabolisms inhibited by the methods can include those responsible for expression of mycotoxins such as aflatoxin. Methods can include inhibition of aflatoxin production without inhibiting fungal growth by contacting a fungus with a suspension including silver nanoparticles that can include a surface coating. The methods can be utilized in preventing fungal-caused destruction of plant species (e.g., crop species). Disclosed methods encompass utilization of silver nanoparticles at low concentrations of from about 10 picograms per liter to about 1 microgram per liter.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF SOUTH CAROLINAOSBORNE ADMINISTRATION BUILDING COLUMBIA SC 29208

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chanda, Anindya Lexington, US 5 3
Lead, Jamie Irmo, US 6 20

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