Method for constructing library of cell-free DNAs in body fluids and application thereof

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United States of America Patent

PATENT NO 12104203
APP PUB NO 20210317516A1
SERIAL NO

16766983

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Abstract

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A method for constructing a library of cell-free DNAs in body fluids, comprising directly acting a transposase or an endonuclease on a body fluid sample, fragmenting the cell-free DNAs within, and performing amplification to obtain a library. Also provided is a test kit using the present method for prenatal diagnosis or early detection of cancer.

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BGI SHENZHENMAIN BUILDING BEISHAN INDUSTRIAL ZONE YANTIAN STREET YANTIAN DISTRICT SHENZHEN 518083

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Chuanyu Shenzhen, CN 5 0
Liu, Longqi Shenzhen, CN 6 0
Shang, Zhouchun Shenzhen, CN 2 0
Wang, Mingyue Shenzhen, CN 25 90
Wu, Liang Shenzhen, CN 154 796
Xu, Jiangshan Shenzhen, CN 2 5
Yuan, Yue Shenzhen, CN 19 45

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