Compounds and methods of promoting myelination
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United States of America
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Oct 1, 2024
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N/A
app pub date -
Apr 17, 2019
filing date -
Apr 17, 2019
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Abstract
A method of promoting the generation of oligodendrocytes from oligodendrocyte precursor cells by enhancing their survival and/or maturation includes administering to the cell an effective amount of an agent that enhances and/or induces accumulation of 8,9-unsaturated sterols in the OPCs, the agent comprising a compound having the formula (I): wherein variables Y1, R1 and R2 are as defined herein.
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