Treatment of fibrosis, cardiovascular disease and heart failure with modified relaxin polypeptides

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 12097242
APP PUB NO 20220331402A1
SERIAL NO

17721569

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Abstract

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The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYPRINCETON NJ

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dubowchik, Gene M Middlefield, US 39 355
Gudmundsson, Olafur S West Windsor, US 5 25
Han, Xiaojun Cheshire, US 32 155
Lawrence, R Michael Yardley, US 68 1038
Lipovsek, Dasa Pepperell, US 81 1800
Madsen, Cort S West Windsor, US 5 25
Mapelli, Claudio Linden, US 42 393
Morin, Paul E Pennington, US 27 301
Myers, Michael C Newtown, US 19 44

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