Pharmaceutical composition containing alkynyl compound and preparation method and application thereof

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United States of America Patent

PATENT NO 12097195
APP PUB NO 20220296587A1
SERIAL NO

17259719

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Abstract

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The present invention relates to a pharmaceutical composition containing alkynyl compound, a preparation method thereof and its application. The present invention discloses a pharmaceutical composition comprising an active pharmaceutical ingredient and an available pharmaceutical excipient; The active pharmaceutical ingredient is 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-benzamide, or its pharmaceutical acceptable salt; The available pharmaceutical excipients includes diluents and lubricants. The pharmaceutical composition can effectively improve the bioavailability of the alkynyl compound, has good dissolution and stability, and improve the drug safety.

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Patent Owner(s)

Patent OwnerAddress
ASCENTAGE PHARMA (SUZHOU) CO LTDUNIT 701 BUILDING B7 218 XINGHU STREET SUZHOU INDUSTRIAL PARK SUZHOU 215000
ASCENTAGE PHARMA GROUP CORP LIMITEDUNIT B 17/F UNITED CENTRE 95 QUEENSWAY ADMIRALTY HONG KONG 999077
HEALTHQUEST PHARMA CO LTDROOM 515 BUILDING F NO 3 LANYUE ROAD HUANGPU DISTRICT GUANGZHOU 510663

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Xiaoling Suzhou, CN 9 52
Huang, Jiaan Suzhou, CN 3 0
Li, Shixiong Suzhou, CN 3 5
Liang, Shihe Suzhou, CN 2 0
Lin, Yanqiong Suzhou, CN 11 0
Wen, Jianfeng Suzhou, CN 20 12
Xu, Feng Suzhou, CN 380 2295

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