Molecular switches

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United States of America

PATENT NO 12091667
SERIAL NO

17454060

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.

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Patent Owner(s)

Patent OwnerAddress
PRECIGEN INC20358 SENECA MEADOWS PARKWAY BLACKSBURG VA 24060

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chao, Lily Yuin Germantown, US 11 2
Dietzel, Kevin Lee Germantown, US 10 0
Held, Mark Anton Germantown, US 9 7
Kealey, James Germantown, US 17 10
Trinh, Na Germantown, US 18 153
Zhao, Xinhua Germantown, US 43 1166

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