Development of spinal cord on a microfluidic chip

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United States of America

PATENT NO 12091650
SERIAL NO

16286185

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Abstract

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The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

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Patent Owner(s)

Patent OwnerAddress
EMULATE INC27 DRYDOCK BOSTON MA 02210

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fraser, Jacob Somerville, US 26 109
Hamilton, Geraldine Boston, US 38 152
Hinojosa, Christopher David Malden, US 74 384
Kerns, S Jordan Reading, US 35 79
Levner, Daniel Brookline, US 140 1266
Lucchesi, Carolina Westwood, US 18 51
Sances, Samuel Santa Monica, US 13 73
Sareen, Dhruv Porter Ranch, US 29 165
Svendsen, Clive Pacific Palisades, US 33 159
Vatine, Gad Los Angeles, US 9 52
Wen, Norman West Roxbury, US 48 248

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