Assessing graft suitability for transplantation

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United States of America

PATENT NO 12084720
SERIAL NO

16954183

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Abstract

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This invention relates to methods and compositions for assessing the suitability of a graft for transplantation or implantation by measuring total and/or specific cell-free nucleic acids (such as cf-DNA) and/or cell lysis. Specifically, the method comprising obtaining an amount of total cf DNA and/or graft-specific cfDNA released from a potential graft (e.g., ex vivo), e.g., prior to contacting of the potential graft with blood cells of a potential recipient, and/or subsequent to contacting of the potential graft or cells thereof with blood cells from a potential recipient, assessing the amount(s) to determine the suitability of the potential graft for transplantation or implantation.

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Patent Owner(s)

Patent OwnerAddress
NATERA INC201 INDUSTRIAL ROAD SUITE 410 SAN CARLOS CA 94070

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mitchell, Aoy Tomita Elm Grove, US 39 1068
Mitchell, Michael Elm Grove, US 159 3092

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