Automated nucleic acid repeat count calling methods

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United States of America Patent

PATENT NO 12080383
APP PUB NO 20200111543A1
SERIAL NO

16659449

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to processes for determining the number of nucleic acid repeats in a DNA fragment comprising a nucleic acid repeat region. One example method may include receiving DNA size and abundance data generated by resolving DNA amplification products. A set of low-pass data may be generated by applying a low-pass filter to the DNA size and abundance data and a set of band-pass data may be generated by applying a band-pass filter to the DNA size and abundance data. A peak of the DNA size and abundance data representative of a number of nucleic acid repeats in the DNA may be identified based on peaks identified from the low-pass data and the band-pass data.

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Patent Owner(s)

  • MYRIAD WOMEN'S HEALTH, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chu, Clement South San Francisco, US 18 385
Evans, Eric A South San Francisco, US 7 41
Haque, Imran S South San Francisco, US 6 12
Patterson, A Scott South San Francisco, US 7 129

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