Personalized pain management and anesthesia: preemptive risk identification and therapeutic decision support

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 12077821
APP PUB NO 20200318194A1
SERIAL NO

16946399

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods and compositions disclosed herein generally relate to methods of improving clinical and economic outcomes to address adverse effects related to anesthesia, analgesics, opioids, and inadequate pain relief. Embodiments of the invention relate to the association between genes, specific polymorphisms of genes, and non-genetic factors with inadequate pain relief and anesthesia-, analgesic, and/or opioid-related adverse effects. Embodiments of the invention can be used to determine and manage patient risk factors for development of adverse perioperative effects and can allow for personalized anesthesia and pain management for improvement of pain control and reduction of anesthesia-, analgesic-, and opioid-related adverse outcomes. These methods and compositions apply to non-surgical pain management with opioids. Therefore, patients who are genetically predisposed to risk of inadequate pain relief and/or serious side effects from anesthesia, analgesics, and/or opioids can be identified and individualized treatment plans developed for implementation by the clinician to improve clinical and economic outcomes.

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Patent Owner(s)

Patent OwnerAddress
CHILDREN'S HOSPITAL MEDICAL CENTER3333 BURNET AVE CINCINNATI OH 45229

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chidambaran, Vidya Cincinnati, US 9 28
Fukuda, Tsuyoshi Cincinnati, US 44 273
McAuliffe, John Cincinnati, US 6 82
Meller, Jaroslaw Cincinnati, US 7 11
Prows, Cynthia A Cincinnati, US 5 31
Sadhasivam, Senthilkumar Mason, US 10 47
Zhang, Kejian Cincinnati, US 17 38

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