Compositions and methods for enhancing production, growth, spread, or oncolytic and immunotherapeutic efficacy of interferon-sensitive viruses

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United States of America Patent

PATENT NO 12076353
APP PUB NO 20200276253A1
SERIAL NO

16763013

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Abstract

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Provided herein are fumaric and maleic acid-containing compounds, compositions comprising the same and methods for using such compounds to enhance production, growth, spread or titer of interferon-sensitive viruses in cells, particularly cancer and tumor cells. Also provided are methods of treating tumors or cancers in a subject by administering the compounds and compositions.

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Patent Owner(s)

Patent OwnerAddress
OTTAWA HOSPITAL RESEARCH INSTITUTEOTTAWA ON K1Y 4E9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arulanandam, Rozanne Orleans, CA 9 5
Diallo, Jean-Simon Ottawa, CA 16 16
Forbes, Nicole Elise Ottawa, CA 2 0
Krishnan, Ramya Hamilton, CA 7 6
Selman, Mohammed Ann Arbor, US 3 0

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