Fusions and method for detecting same

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United States of America Patent

PATENT NO 12055538
APP PUB NO 20210140943A1
SERIAL NO

17144776

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Abstract

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It is intended to reveal a polynucleotide serving as a novel causative gene of a cancer and, on the basis of this finding, to provide a method for detecting the polynucleotide or a polypeptide encoded thereby, a kit and a primer set for the detection, a method for screening for a substance that inhibits the polypeptide, and a pharmaceutical composition for the treatment of a cancer, containing the inhibiting substance. The detection method of the present invention detects a BRAF fusion protein or a fusion gene encoding the fusion protein, or a PXN or GMDS fusion protein or a fusion gene encoding the fusion protein in a digestive organ-derived sample obtained from a subject.

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Patent Owner(s)

Patent OwnerAddress
JAPANESE FOUNDATION FOR CANCER RESEARCH8-31 ARIAKE 3-CHOME KOTO-KU TOKYO 1358550 ?1358550

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fujita, Naoya Tokyo, JP 27 65
Katayama, Ryohei Tokyo, JP 11 7
Sakata, Seiji Tokyo, JP 13 192
Takeuchi, Kengo Tokyo, JP 50 231
Togashi, Yuki Tokyo, JP 11 66

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