Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction

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United States of America Patent

PATENT NO 12054478
APP PUB NO 20230098016A1
SERIAL NO

17944757

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Abstract

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The present disclosure relates to the field of medicinal chemistry, in particular to a phenyl triazole MLL1-WDR5 protein-protein interaction inhibitor (I) and a preparation method thereof, and pharmacodynamics experiments prove that the compound of the present disclosure has relatively strong MLL1-WDR5 protein-protein interaction inhibition activity.

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Patent OwnerAddress
CHINA PHARMACEUTICAL UNIVERSITYNANJING CITY JIANGSU PROVINCE TONG LANE 210009 NO 24 NANJING CITY JIANGSU PROVINCE 210009

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Weilin Nanjing, CN 21 133
Guo, Xiaoke Nanjing, CN 10 7
Li, Dongdong Nanjing, CN 41 159
Wang, Zhihui Nanjing, CN 98 247
You, Qidong Nanjing, CN 14 8

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