Multispecific antigen-binding proteins

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United States of America Patent

PATENT NO 12053525
APP PUB NO 20220409725A1
SERIAL NO

17395400

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.

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Patent Owner(s)

  • GENENTECH, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carter, Paul Hillsborough, US 78 1175
Corn, Jacob Berkeley, US 10 11
Dillon, Michael San Francisco, US 36 1072
Sandoval, Wendy San Bruno, US 3 5
Spiess, Christoph Mountain View, US 32 244
Yin, Yiyuan Fremont, US 14 18
Zhou, Jianhui Redwood City, US 42 439

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