Simultaneous detection of protein isoforms and nucleic acids from low starting cell numbers

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United States of America Patent

PATENT NO 12038407
APP PUB NO 20210278367A1
SERIAL NO

17327806

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Abstract

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Dual nucleic acid and protein isoform measurements are performed on low starting cell numbers (e.g. equivalent to the number of blastomeres composing early embryonic development stages (morula and blastocysts)), comprising integrating fractionation polyacrylamide gel electrophoresis (fPAGE) of 10-100 cells with off-chip analysis of nucleic acids in the nuclei.

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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET TWELFTH FLOOR OAKLAND CA 94607-5200

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
He, Lin Berkeley, US 148 1502
Herr, Amy E Berkeley, US 28 247
Modzelewski, Andrew J Berkeley, US 2 4
Rosàs-Canyelles, Elisabet Berkeley, US 2 0

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