Method for obtaining dissectates microscopic sample, laser microdissection system and computer program

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United States of America Patent

PATENT NO 12038357
APP PUB NO 20220276136A1
SERIAL NO

17667580

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Abstract

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A method for obtaining dissectates from a microscopic sample using a laser microdissection system having a laser unit includes: a) at least partially circumcising and releasing from the sample dissectate regions of the sample as the dissectates using laser pulses provided by the laser unit; b) transferring the dissectates, by being released from the sample, along dissectate trajectories into receptacles of a dissectate collection unit; and c) positioning the receptacles of a dissectate collection unit using a positioning unit to collect the dissectates. The positioning of the receptacles of the dissectate collection unit using the positioning unit is automatically performed based on estimates of the dissectate trajectories, the estimates of the dissectate trajectories being obtained in a learning mode, the learning mode including obtaining dissectates by repeatedly performing at least steps a) and b). Parameters of the dissectate trajectories are determined for a plurality of dissectates.

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Patent Owner(s)

Patent OwnerAddress
LEICA MICROSYSTEMS CMS GMBH68165 MANNHEIM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greb, Christoph Marburg, DE 2 0
Hoffmann, Florian Giessen, DE 31 211
Schlaudraff, Falk Butzbach, DE 26 73

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