Non-chromatographic purification of macrocyclic peptides by a resin catch and release

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United States of America Patent

PATENT NO 12018097
APP PUB NO 20240051996A1
SERIAL NO

17943532

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Abstract

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The disclosure is directed to the synthesis and improved methods for purifying macrocyclic peptides produced by solid phase peptide synthesis. The synthesized peptide is capped with an alkyne-functionalized or azide-functionalized compound of formula (I):

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYPRINCETON NJ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Carter, Percy H Princeton, US 39 228
Creech, Gardner S North Holland, NL 2 1
Eastgate, Martin D Titusville, US 27 31
Kheirabadi, Mahboubeh Cambridge, US 10 3
Nirschl, David S Yardley, US 2 1

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