Pyrido[2,3-d]pyrimidin-7-ones and related compounds as inhibitors of protein kinases

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United States of America

PATENT NO 12012402
SERIAL NO

17499995

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Abstract

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Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 could provide therapeutic benefit.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF HOUSTON SYSTEM4800 CALHOUN ROAD HOUSTON TX 77204-2015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cuny, Gregory Houston, US 6 3
Degterev, Alexei Brookline, US 27 291
Nikhar, Sameer Houston, US 3 0

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