Fluidic devices with reaction wells and constriction channels and uses thereof
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United States of America Patent
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Jun 4, 2024
Grant Date -
Aug 25, 2022
app pub date -
Oct 25, 2019
filing date -
Oct 26, 2018
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Abstract
The present disclosure provides fluidic devices and fluidic device assemblies, including microfluidic devices and cartridges comprising the same, that in illustrative embodiments, can be used to make particles or protein precipitates, or to monitor precipitate formation. The fluidic devices typically include channels that connect a reaction well to an inlet port and an outlet port, and a fluidic constriction channel that is configured to help retain fluids in the reaction well and/or promote mixing within the reaction well. In some aspect, fluidic devices are interconnected into fluidic assemblies that can be used in continuous process methods.
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