Calicheamicin derivatives and antibody drug conjugates thereof

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United States of America Patent

PATENT NO 11993625
APP PUB NO 20190345186A1
SERIAL NO

16477290

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Abstract

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The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.

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Patent Owner(s)

Patent OwnerAddress
PFIZER INC235 EAST 42ND STREET NEW YORK NY 10017

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahmad, Omar Khaled Providence, US 6 6
Brown, Stephen Paul Mystic, US 2 1
Dirico, Kenneth John Gales Ferry, US 5 18
Dushin, Russell Old Lyme, US 27 122
Filzen, Gary Frederick Schwenksville, US 5 9
Puthenveetil, Sujiet Franklin, US 7 36
Strop, Pavel San Mateo, US 43 756
Subramanyam, Chakrapani South Glastonbury, US 75 646
Tumey, Lawrence N Pawcatuck, US 10 35

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