Prefusion RSV F proteins and their use

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11981707
APP PUB NO 20240018193A1
SERIAL NO

18464786

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Abstract

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Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boyington, Jeffrey Clarksburg, US 14 101
Chen, Lei Rockville, US 979 4055
Chen, Man Clarksburg, US 30 102
Chuang, Gwo-Yu Rockville, US 23 84
Georgiev, Ivelin Stefanov Nashville, US 17 86
Gorman, Jason Silver Spring, US 14 123
Graham, Barney S Smyrna, US 32 157
Joyce, Michael Gordon Washington, US 33 195
Kanekiyo, Masaru North Bethesda, US 40 238
Kwong, Peter D Washington, US 48 271
McLellan, Jason S Austin, US 7 76
Ofek, Gilad Gaithersburg, US 14 76
Pancera, Marie Seattle, US 17 112
Sastry, Mallika Rockville, US 10 53
Soto, Cinque Rockville, US 8 86
Srivatsan, Sanjay Lilburn, US 7 86
Stewart-Jones, Guillaume Cambridge, US 36 160
Yang, Yongping Potomac, US 33 106
Zhang, Baoshan Bethesda, US 35 163
Zhou, Tongqing Boyds, US 44 202

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