Implantable and biodegradable smart hydrogel micromechanical resonators with ultrasound readout for biomedical sensing

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United States of America

PATENT NO 11980498
SERIAL NO

17315039

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Abstract

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Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency. Such change can be correlated to concentration of the analyte.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF UTAH RESEARCH FOUNDATION615 ARAPEEN DRIVE SUITE 310 SALT LAKE CITY UT 84108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blair, Steven M Salt Lake City, US 34 364
Farhoudi, Navid Salt Lake City, US 6 4
Kairy, Prattay Deepta Salt Lake City, US 2 0
Laurentius, Lars B Cottonwood Heights, US 3 0
Magda, Jules J Salt Lake City, US 5 610
Reiche, Christopher F Salt Lake City, US 8 4
Solzbacher, Florian Salt Lake City, US 32 264

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