Bicyclic peptide ligands specific for transferrin receptor 1 (TfR1)

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11970555
SERIAL NO

17454665

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which bind to TfR1. The invention also relates to multimeric binding complexes which comprise at least two of said bicyclic peptide ligands. The invention also includes pharmaceutical compositions comprising said peptide ligands and multimeric binding complexes and the use of said peptide ligands, and multimeric binding complexes and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder through TfR1 mediated delivery of a therapeutic agent.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
BICYCLETX LIMITEDBLOCKS A&B PORTWAY BUILDING GRANTA PARK GREAT ABINGTON CAMBRIDGE CB21 6GS

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gowans, Ellen Cambridge, GB 3 0
Mudd, Gemma Elizabeth Cambridge, GB 16 94
Rigby, Michael Cambridge, GB 19 70
Seth, Punit Carlsbad, US 5 14
Skynner, Michael Cambridge, GB 22 79
Stanway, Steven Cambridge, GB 4 0
Urbonas, Liudvikas Cambridge, GB 3 0
Van, Rietschoten Katerine Cambridge, GB 26 130

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
3.5 Year Payment $1600.00 $800.00 $400.00 Oct 30, 2027
7.5 Year Payment $3600.00 $1800.00 $900.00 Oct 30, 2031
11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 30, 2035
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00