Engineered protease variants

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11959108
SERIAL NO

17460141

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Abstract

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The present invention provides engineered protease polypeptides and compositions thereof. The engineered protease polypeptides have been optimized to provide improved activity, improved thermostability, protease stability, autolytic stability, and stability under a range of pH conditions, including acidic (pH<7) and basic (pH>7) conditions. The invention also relates to the use of the compositions comprising the engineered protease polypeptides for therapeutic and/or nutritional purposes. The present invention also provides polynucleotides encoding the engineered protease polypeptides, as well as methods for making the engineered polynucleotides and protease polypeptides.

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Patent Owner(s)

Patent OwnerAddress
CODEXIS INC200 PENOBSCOT DRIVE REDWOOD CITY CA 94063

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alaoui, Ismaili Moulay Hicham San Mateo, US 8 7
Chng, Chinping Menlo Park, US 25 32
Dellas, Nikki San Carlos, US 61 39
Garcia, Ravi David Los Gatos, US 20 8
McCluskie, Kerryn Pacifica, US 6 2
Vallieu, Kristen Jean Union City, US 10 10

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