Bifidobacterium lactis strain for preventing or treating colitis and method for preventing or alleviating colitis

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United States of America Patent

PATENT NO 11959067
APP PUB NO 20230069454A1
SERIAL NO

17900862

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The present disclosure provides a Bifidobacterium lactis (B. lactis) strain XLTG11 and a use thereof. The strain belongs to Bifidobacterium lactis. The B. lactis strain XLTG11 was deposited in the China General Microbiological Culture Collection Center (CGMCC) on Oct. 25, 2019, with a taxonomic name of Bifidobacterium lactis XLTG11 and an accession number of CGMCC No. 18738. The B. lactis strain XLTG11 provided by the present disclosure can regulate an inflammatory cytokine, improve an intestinal barrier function, and modulate an intestinal flora by inhibiting the activation of a TLR4/MYD88/NF-κB signaling pathway, thereby alleviating dextran sulfate sodium (DSS)-induced colitis. In addition, the B. lactis strain XLTG11 has an immune-enhancing effect on a cyclophosphamide (CTX)-induced mouse immunosuppression model.

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Patent OwnerAddress
HARBIN SUNFLOWER PHARMACEUTICAL CO LTD150078 OFFICE SCIENTIFIC RESEARCH CENTER NO 18 DONGHU ROAD YINGBIN ROAD CLUSTER HARBIN HI TECH INDUSTRIAL DEVELOPMENT ZONE HEILONGJIANG PROVINCE HARBIN CITY HEILONGJIANG PROVINCE 150078

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Inventor Name Address # of filed Patents Total Citations
Guan, Yanbin Longjiang, CN 3 1

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