Treatment of infections and biofilm formation using a cellulose synthase inhibitor
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United States of America Patent
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Mar 26, 2024
Grant Date -
Oct 21, 2021
app pub date -
Apr 2, 2021
filing date -
Apr 15, 2020
priority date (Note) -
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status (Latency Note)
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Abstract
In one embodiment, the present application relates to methods and materials for weed control of a field of a crop plant using a cellulose biosynthesis inhibitor selected from the group consisting of ES20 and ES20-1 to ES20-9 of FIG. 1A. In another embodiment, the present disclosure relates to a method for treatment or prevention of an infection through inhibition of biofilm formation of microorganisms comprising the step of applying a therapeutic effective amount of a cellulose biosynthesis inhibitor selected from the group consisting of ES20 and ES20-1˜ES20-9 of FIG. 1A, or a salt thereof, in combination with one or more other commonly used antibiotics. A composition matter comprising said compounds and methods of use are within the scope of the present invention.
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