Trispecific and/or trivalent binding proteins

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11932704
SERIAL NO

17515227

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Abstract

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The disclosure provides trispecific and/or trivalent binding proteins comprising four polypeptide chains that form three antigen binding sites that specifically bind one or more target proteins, wherein a first pair of polypeptides forming the binding protein possess dual variable domains having a cross-over orientation and wherein a second pair of polypeptides forming the binding protein possess a single variable domain. The disclosure also provides methods for making trispecific and/or trivalent binding proteins and uses of such binding proteins.

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Patent Owner(s)

  • SANOFI - AVENTIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beil, Christian Frankfurt Am Main, DE 29 255
Beninga, Jochen Frankfurt Am Main, DE 16 82
Corvey, Carsten Frankfurt am Main, DE 25 294
Lange, Christian Frankfurt am Main, DE 81 531
Leuschner, Wulf Dirk Frankfurt Am Main, DE 8 71
Nabel, Gary J Cambridge, US 131 4161
Rao, Ercole Frankfurt Am Main, DE 59 535
Seung, Edward Cambridge, US 15 104
Wei, Ronnie Needham, US 29 216
Wu, Lan Cambridge, US 22 161
Yang, Zhi-Yong Cambridge, US 61 517

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