Therapeutical tools and methods for treating blindness by targeting photoreceptors
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United States of America Patent
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Mar 19, 2024
Grant Date -
Mar 25, 2021
app pub date -
Oct 30, 2020
filing date -
Sep 15, 2015
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Abstract
The present inventions relates to an isolated nucleic acid molecule comprising a nucleotide sequence coding for a depolarizing light-gated ion channel functionally linked to a promoter leading to the specific expression of said depolarizing light-gated ion channel in a retinal photoreceptor, or the nucleotide sequence complementary to said nucleotide sequence, for use in treating or ameliorating blindness. The present invention also relates to methods of using such nucleic acid molecules in the treatment of blindness.
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