Antibody-cytokine engrafted proteins and methods of use for immune related disorders

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United States of America Patent

PATENT NO 11930837
APP PUB NO 20220039441A1
SERIAL NO

17403710

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Abstract

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The present disclosure provides antibody cytokine engrafted proteins that bind to and stimulate intracellular signaling through a high affinity interleukin receptor. The antibody cytokine engrafted proteins find use in enhancing anti-inflammatory cell responses, and reducing pro-inflammatory effects in the treatment, amelioration and prevention of immune related disorders such as Type 1 Diabetes.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Diaz-De-Durana, Yaiza San Diego, US 5 1
DiDonato, Michael San Diego, US 13 3
Filippi, Christophe Studio City, US 5 1
Meeusen, Shelly Rancho Santa Fe, US 6 0
Spraggon, Glen San Diego, US 17 27

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