Bioconversion of short-chain hydrocarbons to fuels and chemicals

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United States of America Patent

PATENT NO 11913049
APP PUB NO 20200347423A1
SERIAL NO

16878032

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Abstract

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An engineered microorganism(s) with novel pathways for the conversion of short-chain hydrocarbons to fuels and chemicals (e.g. carboxylic acids, alcohols, hydrocarbons, and their alpha-, beta-, and omega-functionalized derivatives) is described. Key to this approach is the use of hydrocarbon activation enzymes able to overcome the high stability and low reactivity of hydrocarbon compounds through the cleavage of an inert C—H bond. Oxygen-dependent or oxygen-independent activation enzymes can be exploited for this purpose, which when combined with appropriate pathways for the conversion of activated hydrocarbons to key metabolic intermediates, enables the generation of product precursors that can subsequently be converted to desired compounds through established pathways. These novel engineered microorganism(s) provide a route for the production of fuels and chemicals from short chain hydrocarbons such as methane, ethane, propane, butane, and pentane.

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Patent Owner(s)

Patent OwnerAddress
GONZALEZ RAMON6314 W MACLAURIN DR TAMPA FL 33647

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chou, Alexander Houston, US 6 0
Clomburg, James Houston, US 8 20
Gonzalez, Ramon Friendswood, US 29 62

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