Non-catalytic substrate-selective p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof

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United States of America Patent

PATENT NO 11911392
APP PUB NO 20220331329A1
SERIAL NO

17740248

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Abstract

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Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

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Patent Owner(s)

  • THE UNIVERSITY OF MARYLAND BALTIMORE; THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hasday, Jeffrey D Timonium, US 9 17
Mackerell,, Jr Alexander D Baltimore, US 25 95
Shapiro, Paul S Baltimore, US 16 167

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