Compounds as neurokinin-1 receptor antagonists and uses thereof

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United States of America Patent

PATENT NO 11905247
SERIAL NO

17476028

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Abstract

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The present invention relates compounds of Formula (A) as NK-1 receptor antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate transmission. The present invention also relates to the uses of the compounds or pharmaceutical compositions in treating or preventing certain disorders and diseases which relate to NK-1 receptor in humans. More specifically, the compounds and/or pharmaceutical compositions of the present invention are believed to potentially offer therapeutic benefits to patients who suffer, among others, chemotherapy-induced nausea and vomit (CINV) and/or post-operative nausea and vomit (PONV).

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Patent Owner(s)

Patent OwnerAddress
XWPHARMA LTDOFFICES OF OFFSHORE INCORPORATIONS (CAYMAN) LIMITED P O BOX 31119 GRAND PAVILION HIBISCUS WAY 802 WEST BAY ROAD GRAND CAYMAN KY1-1205

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eng, Wai-Si Maple Glen, US 17 355
Feng, Yi Wuhan, CN 82 822
Liu, Xianbo Wuhan, CN 10 188
Xiang, Jia-Ning Fremont, US 107 1611
Xu, Xuesong Wuhan, CN 45 819

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