Removal of serine proteases by treatment with finely divided silicon dioxide

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United States of America Patent

PATENT NO 11891431
APP PUB NO 20210139562A1
SERIAL NO

17103618

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Abstract

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The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for manufacturing plasma-derived protein compositions having reduced serine protease and\or serine protease zymogen content. Among yet other aspects, the present invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced serine protease and/or serine protease zymogen content. Yet other aspects include methods for treating, managing, and/or preventing a disease comprising the administration of a plasma-derived protein composition having a reduced serine protease or serine protease zymogen content.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA 541-8645

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Madlener, Ruth Kennelbach, AT 13 67
Pljevljakovic, Azra Vienna, AT 22 117
Schwarz, Hans-Peter Vienna, AT 143 1170
Svatos, Sonja Berg, AT 21 175
Teschner, Wolfgang Vienna, AT 52 519
Weber, Alfred Vienna, AT 70 334

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