Synthetic 5' UTR sequences, and high-throughput engineering and screening thereof

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United States of America Patent

PATENT NO 11875876
SERIAL NO

16441647

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Abstract

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Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts. Also disclosed herein are methods of engineering 5′ UTR sequences and methods and kits for screening 5′ UTR sequences for a property of interest.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cao, Jicong Cambridge, US 2 1
Kellis, Manolis Boston, US 9 98
Lu, Timothy Kuan-Ta Cambridge, US 84 571
Novoa, Pardo Eva Maria Cambridge, US 1 1
Zhang, Zhizhuo Cambridge, US 7 107

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