2,2-difluoropropionamide derivatives of bardoxolone methyl, polymorphic forms and methods of use thereof

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United States of America Patent

PATENT NO 11873320
SERIAL NO

17444594

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Abstract

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The present invention relates generally to the compound:

    N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide,polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

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Patent Owner(s)

Patent OwnerAddress
REATA PHARMACEUTICALS HOLDINGS LLC5320 LEGACY DRIVE PLANO TX 75024

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mattei, Alessandra Chicago, US 6 29
Sheikh, Ahmad Y Deerfield, US 55 561
Wang, Xiu C Green Oaks, US 24 54

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