Anti-CEACAM6 antibodies and uses thereof

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United States of America Patent

PATENT NO 11866495
APP PUB NO 20200157214A1
SERIAL NO

16776329

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Abstract

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The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for human and Macaca fascicularis CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, Non-specific crossreacting antigen, NCA, NCA-50/90), and which do not significantly cross-react with the closely related human CEACAM1, human CEACAM3, and human CEACAM5. The invention further provides methods to generate this kind of antibodies.

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Patent Owner(s)

  • DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beckhove, Philip Heidelberg, DE 3 3
Dittmer, Frank Düsseldorf, DE 21 78
Freiberg, Christoph Wuppertal, DE 19 150
Ge, Yingzi Wiesloch, DE 3 3
Glück, Julian Marius Meerbusch, DE 5 24
Golfier, Sven Berlin, DE 19 107
Gritzan, Uwe Cologne, DE 23 96
Gutierrez, Eva-Maria Illertissen, DE 3 3
Holton, Simon Berlin, DE 36 83
Pinkert, Jessica Wuppertal, DE 3 3
Schönfeld, Dorian Cologne, DE 6 14
Trautwein, Mark Whippany, US 26 180
Willuda, Jörg Glienicke/Nordbahn, DE 16 73

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