Antibody specifically binding to FOLR1 and uses thereof

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United States of America Patent

PATENT NO 11866492
APP PUB NO 20210009685A1
SERIAL NO

16980074

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Abstract

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A modified antibody that binds specifically to folate receptor alpha (FOLR1) and blocks the activity of FOLR1 with an increased binding affinity, an antigen-binding fragment thereof, a composition containing the antibody or fragment, and their uses are disclosed. The modified antibody or antigen-binding fragment thereof may be used for the prevention or treatment of cancer proliferative disorder associated with an increased FOR1 expression, and may also be used for diagnosis of the disease. The proliferative disorder may be cancer.

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Patent Owner(s)

Patent OwnerAddress
ALTEOGEN INCDAEJEON DAEJEON

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chung, Hye-Shin Daejeon, KR 13 95
Lee, Sunbae Daejeon, KR 5 38
Park, Soon Jae Daejeon, KR 21 105

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