Synthetic single domain antibody

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United States of America Patent

PATENT NO 11866484
APP PUB NO 20210347855A1
SERIAL NO

17190626

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Abstract

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The invention relates to the identification of a highly stable single domain antibody scaffold (hs2dAb) and its use in generating synthetic single domain antibody library (hs2dAb-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT CURIE26 RUE D'ULM 75005 PARIS 75005
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS 75016
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE PAUL SABATIER TOULOUSE III118 ROUTE DE NARBONNE 31062 TOULOUSE CEDEX 9

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Moutel, Sandrine Paris, FR 9 12
Olichon, Aurelien Toulouse, FR 8 2
Perez, Franck Paris, FR 20 17

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