Panaxadiol glycoside derivative and preparation method and application thereof

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United States of America Patent

PATENT NO 11866458
APP PUB NO 20210054019A1
SERIAL NO

16764090

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Abstract

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The invention discloses a panaxadiol glycoside derivative and a preparation method and application thereof. Such compounds show strong anti-inflammatory effects in vitro and in animal model experiments, and thus can be used to prepare anti-inflammatory drugs, especially can be used for treating asthma and COPD. In the experiment, the above-mentioned compounds have obvious effects on asthma and COPD, and the efficacy of the high-dose group is superior than that of dexamethasone and budesonide. Even under the dose much exceeding the therapeutic dose, no obvious affect on blood routine and blood glucoseis observed. It has high industrial prospects in the field of anti-inflammatory drugs, especially in the field for treating asthma and COPD.

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Patent Owner(s)

Patent OwnerAddress
SUZHOU JI ER BIOLOGICAL MEDICINE CO LTD2A 270 DONGPING STREET SUZHOU INDUSTRIAL PARK JIANGSU 215000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liu, Quanhai Shanghai, CN 13 13
Zhang, Jun Shanghai, CN 1152 7034

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