Lyophilized polymer scaffold compositions, processes for preparation and use in anabolic wound repair
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United States of America Patent
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Dec 19, 2023
Grant Date -
Mar 2, 2017
app pub date -
Feb 20, 2015
filing date -
Feb 20, 2014
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Abstract
The present application relates to a lyophilized scaffold composition having at least one polysaccharide wherein said scaffold is substantially solid and capable of being formed into a desired shape; wherein the at least one polysaccharide has a protonation level resulting in controlled rehydration of said scaffold, such that when said scaffold is contacted with at least one of a neutral aqueous solution, blood, blood derived fluid and combinations thereof, said scaffold forms a microparticle dispersion and stimulates tissue remodeling and anabolic wound repair, a process for preparing a lyophilized scaffold composition and the use of a lyophilized scaffold composition for wound repair in a mammal.
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