Classification of nucleic acid templates
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United States of America Patent
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Dec 19, 2023
Grant Date -
Aug 24, 2023
app pub date -
Mar 23, 2023
filing date -
Dec 11, 2008
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Abstract
Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
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