Use of bromophenol-pyrazoline compounds for the treatment of feline coronavirus diseases

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United States of America Patent

PATENT NO 11840518
APP PUB NO 20220363644A1
SERIAL NO

17869819

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Abstract

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The present invention belongs to the field of medical technology, and specifically relates to use of bromophenol-pyrazoline compounds for the treatment of feline coronavirus diseases. Studies carried out for the present invention revealed that bromophenol-pyrazoline compounds could inhibit activity of feline infectious peritonitis virus main protease (FIPV Mpro) and interfere with replication of feline infectious peritonitis virus (FIPV) in cells. In a clinical trial, the bromophenol-pyrazoline compounds can treat infectious peritonitis in cats naturally infected with the FIPV, greatly improve survival rate of cats, and can be used to prepare drugs for treating feline infectious peritonitis.

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Patent Owner(s)

Patent OwnerAddress
SHANDONG LINGHAI BIOTECHNOLOGY CO LTDWEIHAI CITY SHANDONG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Xiangqian Weihai, CN 18 29
Shi, Dayong Weihai, CN 5 2
Wang, Xin Weihai, CN 1487 14353
Xu, Feng Weihai, CN 380 2295

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