Alkynylphenylbenzamide compounds and applications thereof

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United States of America Patent

PATENT NO 11834454
APP PUB NO 20230046126A1
SERIAL NO

17948236

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Abstract

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The present disclosure relates to Alkynylphenylbenzamide compounds and the applications thereof. The said Alkynylphenylbenzamide compounds have the structure shown in Formula (I). The compounds can be used as protein kinase inhibitors, which can effectively inhibit the activity of TRK protein kinase and the proliferation, migration and invasion of various tumor cells. At the same time, it has the characteristics of good pharmacokinetics and low toxicity.

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Patent Owner(s)

Patent OwnerAddress
SHENZHEN NEWDEL BIOTECH CO LTDA1503 BUILDING 1 PHASE II YESUN INTELLIGENT NO 1301-76 GUANGUANG ROAD XINLAN COMMUNITY GUANLAN SUB-DISTRICT LONGHUA DISTRICT SHENZHEN GUANGDONG 518110 518110

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Ke Guangdong, CN 83 511
He, Xun Guangdong, CN 9 44
Jin, Feng Guangdong, CN 106 619
Li, Zhenwei Guangdong, CN 15 5
Lu, Xiaoyun Guangdong, CN 12 25
Tang, Xia Guangdong, CN 96 415
Tu, Zhengchao Guangdong, CN 14 29
Wang, Jie Guangdong, CN 397 3465
Wang, Zuqin Guangdong, CN 1 0
Xiang, Shuang Guangdong, CN 3 0
Zhang, Shuihua Guangdong, CN 1 0
Zhang, Zhang Guangdong, CN 221 2480
Zhang, Zhimin Guangdong, CN 44 425

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