Composition and methods for preventing or reducing the incidence of transient ischemic attacks

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United States of America Patent

PATENT NO 11826366
SERIAL NO

17452995

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Abstract

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A composition and method for preventing or reducing the incidence of a transient ischemic attack in a subject at risk for developing a stroke comprises orally administering to the subject a prophylactically effective amount of a pharmaceutical composition comprising an ASIC1a inhibitor capable of penetrating the blood-brain barrier. Preferred ASIC1a inhibitors for use in the disclosed methods include amiloride and amiloride analogs.

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Patent Owner(s)

Patent OwnerAddress
MOREHOUSE SCHOOL OF MEDICINE720 WESTVIEW DRIVE SW ATLANTA GA 30310-1495

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Simon, Roger P Atlanta, US 25 176
Xiong, Zhigang Atlanta, US 21 139

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