Method for preparing a large animal model with peritoneal carcinomatosis

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United States of America Patent

PATENT NO 11825818
APP PUB NO 20210051926A1
SERIAL NO

16846321

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Abstract

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The present invention relates to a method for preparing a large animal model, with peritoneal carcinomatosis, which is an abdominal cavity metastasis of tumor commonly found in advanced or recurrent solid cancer, is induced using a large animal, and the method for preparing a large animal model with peritoneal carcinomatosis comprises injecting a cancer cell line into the abdominal cavity of a piglet in which the immune function is not completed. The method for preparing a large animal model with peritoneal carcinomatosis, when a human-derived immortalized cell line is inoculated into a pig, can overcome xenograft rejection and induce peritoneal carcinomatosis, can use animals with sufficient supply and demand, and can expect the spread of peritoneal carcinomatosis through breeding.

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Patent Owner(s)

Patent OwnerAddress
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONSEOUL NATIONAL UNIVERSITY 1 GWANAK-RO GWANAK-GU SEOUL 151-744
SEOUL NATIONAL UNIVERSITY HOSPITAL101 DAEHAK-RO JONGNO-GU SEOUL 03080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Ji Yeon Seoul, KR 6 10
Kim, Hee Seung Seoul, KR 87 472
Lee, Eun Ji Seoul, KR 26 181
Lee, Na Ra Seoul, KR 5 1
Lee, Sung Jong Seoul, KR 3 23
Lim, Jeong Mook Seoul, KR 23 142
Park, Soo Jin Seoul, KR 53 207

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